Prof. MUDr. Radim J. SRAM, DrSc.

IEM AS CR, v.v.i., Prague, Czech Republic, EU

Specialization: Ecotoxicology, Impact of air pollution and smoking on human body

Dr. Sram received his M.D.  at the Medical Faculty, Charles University, Prague (1964), Ph.D. (1970) at the Czechoslovak Academy of Sciences, Prague, on studies on chemical mutagenesis. He was introduced to this field of study by Prof. Charlotte Auerbach, Department of Genetics, University of Edinburgh, UK (1968-1969). He received his D.Sc. in the field of Medical Genetics at Charles University, Prague (1978).

In 1990, he established the Teplice Program (The impact of environmental pollution on the health of human population) as international program collaborating with US EPA and various laboratories in EU. The Teplice Program became the unique program (probably in all Europe) analyzing the effect of high pollution using various biomarkers of exposure and effects.  It became the project where various methods of molecular epidemiology were used. In those studies were proved the relationships between the effect of exposure to carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) and DNA adducts and chromosome aberrations in lymphocytes and placentas, which were also analyzed according to genotypes. Combining the results of epidemiological studies proving the impact of increase in concentrations of PM10 and c-PAHs on intrauterine growth retardation with methods of molecular epidemiology those studies are probably one of very rare complex studies about the effect of pollutants on genetic material in Europe.

During the last years, he started to study the impact of air pollution, especially c-PAHs (Program Ostrava) to children health (asthma bronchiale) using the chip technology to determine genetic polymorphisms and gene expression, to volunteers using biomarkers, as well as the impact of smoking on pregnancy outcomes.

He has more than 250 publications in peer-reviewed journals, HI=33. He organized several EEMS, ICEMHP, or other international meetings related to genetic toxicology or molecular epidemiology.

Between 1993-1995 he was the President of EEMS (European Environmental Mutagen Society), he received EEMS Frits Sobels Prize for 2000. He organized several EEMS, ICEMHP, or other international meetings related to genetic toxicology or molecular epidemiology.

At the NANOCON 2012 conference Dr. Sram will present the invited lecture in the Session D-Health, safety and environment challenges.

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